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- Patient Reported Outcomes
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- Disease Strategy
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- eHealthcare
- Formulation
- Hit-to-Lead
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- Pharmacovigilance
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Rethinking the Role of Life Sciences Companies in the Healthcare Ecosystem
iHealth Connections, 2011;1(2):103-7
Abstract
The life sciences industry stands at a crossroads. Its business model is broken and the environment in which it operates is changing dramatically. So how should companies respond? They can carry on as normal, at the risk of fading into insignificance, or completely rethink how they engage with the other stakeholders in the healthcare ecosystem, i.e. all the entities—be they other life sciences companies, individuals, governments, healthcare providers or insurers—that help keep people healthy.
Disclosure
The authors are employed by IBM Global Business Services, which develops fact-based strategic insights on critical public and private sector issues for senior executives via the IBM Institute for Business Value. This article is based on an in-depth study by the Institute’s research team.
Correspondence:
hfraser@uk.ibm.com
The challenges the life sciences industry faces have been thoroughly documented. Its scientific productivity has declined. The blockbusters on which it has long relied for its prosperity are coming off patent (see Figure 1). The regulations governing drug development and manufacturing are becoming more onerous. And the promotional practices it engages in are attracting greater scrutiny, with a growing number of doctors in the mature economies refusing to take sales calls.1
As if this was not enough to contend with, social, economic, and technological forces are also reshaping the healthcare ecosystem in which the industry works. The global population is aging.2 The incidence of chronic disease is rising.3 Patients are becoming more demanding. Plus new technologies and treatments are driving already high healthcare costs even higher.
Many governments have responded by trying to curb the soaring healthcare bill while improving access to care. Countries with socialized systems are transferring a bigger share of the burden to individual citizens. For example, in 2010, Germany passed a law increasing premiums for the country’s 72 million people with state health insurance.4 Conversely, countries with market-based systems are digging into the public coffers. The US is one such instance; the Affordable Care Act 2010, which aims to help the poor and elderly, will cost an estimated US$938 billion.5
Meanwhile, the medical community is pioneering new modes of healthcare delivery based on the continuous management of disease rather than expensive episodic care. Healthcare providers everywhere are also investing in electronic medical record systems, which will enable them to study how genetic variations, differences in treatment, and the like, have a bearing on disease.6
In addition, new entities—many of them from industries that have not previously played a role in healthcare—are entering the arena. Some of these entities, such as 23andMe,7 are changing the way in which diseases are identified and treated. Others are creating value through new business models, one such example being Dossia, a consortium of US companies that uses its collective influence to give employees better access to health information.8
References:
- IBM Institute for Business Value, Fade or flourish? Rethinking the role of life sciences companies in the healthcare ecosystem, August 2011. Available at: www-935.ibm.com/services/us/gbs/thoughtleadership/ibv-lifesciences-fade-flourish.html (accessed September 26, 2011).
- United Nations, Department of Economic and Social Affairs, Population Division, World Population Prospects: The 2008 Revision, New York: United Nations, 2009.
- World Health Organization, Preventing chronic disease: a vital investment, Geneva: WHO, 2005.
- Kirschbaum E, Germany passes unpopular healthcare reform, Reuters, November 12, 2010.
- US Congressional Budget Office, H.R. 4872, Reconciliation Act of 2010 (Final Health Care Legislation), March 20, 2010. Available at: www.cbo.gov/doc.cfm?index=11379 (accessed September 26, 2011).
- Suwinksi P, Health Information Technologies: Market Overviews and Trends, Presented at: 2nd Annual Asia Electronic Health Records Conference, Singapore, 2010.
- 23andMe website. Available at: https://www.23andme.com (accessed September 26, 2011).
- Dossia website. Available at: www.dossia.org/aboutdossia/an-introduction-to-dossia (accessed September 26, 2011).
- Capital IQ database 2011. Available at: www.capitaliq.com/home.aspx (accessed October 3, 2011). Approval for use from William P Porter, Capital IQ.
- Munos B. Lessons from 60 years of pharmaceutical innovation, Nat Rev Drug Discov 2009;8(12):959–68.
- eKnowledgeBase 2010. Available at: www.eknowledgbase.com (accessed October 3, 2011). Approval for use from Glenn Glasberg, UBM.
- Armstrong W. Pharma’s Orphans, Pharmaceutical Executive, May 1, 2010. Available at: http://pharmexec.findpharma.com/pharmexec/article/articleDetail.jsp?id=670568&sk=&date=&pageID=4 (accessed September 26, 2011).
- Globocan 2008 statistics. Available at: http://globocan.iarc.fr/factsheets/populations/factsheet.asp?uno=900#KEY (accessed October 3, 2011).
- Campbell D, Chui M, Pharmerging shake-up—New imperatives in a redefined world, IMS Health 2010.
- Martino M, 2010 Pharma job cuts cross the 50K mark, FiercePharma, December 1, 2010.
- Korsten P, Seider C, The world’s 4 trillion dollar challenge— Using a system-of-systems approach to build a smarter planet, IBM Institute for Business Value, January 2010. Available at: http://public.dhe.ibm.com/common/ssi/ecm/en/gbe03278usen/GBE03278USEN.PDF (accessed October 3, 2011).
- Pfizer rises on talk it will sell-off huge chunk of non-core businesses, The Pharma Letter, March 15, 2011.
- Abbott website. Available at: www.abbott.com/global/url/content/en_US/20.20:20/product/Products_By_Category.htm (accessed October 3, 2011).
- Johnson & Johnson website. Available at: www.jnj.com/connect/healthcare-products (accessed September 26, 2011).
- Evaluate Pharma, World Preview 2016, May 2010. Available at: www.evaluatepharma.com/EvaluatePharma_World_Preview_2016.aspx (accessed October 3, 2011).
- Grogan K, Merck & Co pulls long-term forecast, committed to R&D, PharmaTimes Online, February 4, 2011. Available at: www.pharmatimes.com/Article/11-02-04/Merck_Co_pulls_longterm_forecast_committed_to_R_D.aspx (accessed October 3, 2011).
- European Commission, FP7 in Brief—How to get involved in the EU 7thFramework Programme for Research, Luxembourg: Office for Official Publications of the European Communities, 2007.
- Stovall S. Europe’s drug regulator says innovation must pick up, The Wall Street Journal, December 15, 2010.
- Carroll J, Pharma giants join forces behind Asian cancer research group, FierceBiotech Research, February 23, 2010.








